Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27465158 | 0.86 | CA12 (0.33) | TSHR | |
| SCHEMBL27654742 | 0.80 | PPARG (0.35) | TSHR | |
| SCHEMBL3741276 | 0.78 | NPC1 (0.41) | — | |
| SCHEMBL6305310 | 0.75 | — | — | |
| SCHEMBL5919315 | 0.72 | MDM4 (0.39) | — | |
| SCHEMBL1287361 | 0.69 | CYP2D6 (0.34) | TSHR | |
| SCHEMBL20335124 | 0.64 | GAA (0.44) | TSHR | |
| SCHEMBL27810673 | 0.61 | SLC7A5 (0.48) | — | |
| SCHEMBL6010216 | 0.61 | KDM4E (0.37) | — | |
| SCHEMBL5080360 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068333-A | Has hydrazine analog derivative of pharmacologically active and preparation method thereof | CIBA GEIGY AG (CH) | 1993-01-27 | — | — | CN | disclosed |