SCHEMBL5080360

SCHEMBL5080360

CC(C)CONC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30035831 0.88 TSHR (0.42)
SCHEMBL878423 0.82
SCHEMBL9104814 0.80 NAMPT (0.48)
SCHEMBL1757197 0.80
SCHEMBL878422 0.78
SCHEMBL1757195 0.78
SCHEMBL27479543 0.76 TSHR (0.39)
SCHEMBL12057478 0.75 TSHR (0.38)
SCHEMBL569638 0.75 TSHR (0.52)
SCHEMBL23067252 0.73 LMNA (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10376591-B2 Formulations and carrier systems including farnesylthiosalicylic moieties University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2019-08-13 US claimed
US-20190038556-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2019-02-07 US claimed
US-20180214563-A1 IMMUNOSTIMULATORY NANOCARRIER PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2018-08-02 US claimed
US-20180000957-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING FARNESYLTHIOSALICYLIC MOIETIES PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2018-01-04 US claimed
US-9855341-B2 Formulations and carrier systems including farnesylthiosalycylic moities University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2018-01-02 US claimed
WO-2017023667-A1 IMMUNOSTIMULATORY NANOCARRIER UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2017-02-09 WO claimed
US-20160128938-A9 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2016-05-12 US claimed
CN-105188673-A Formulations and carrier systems including compound interactive domains UNIV PITTSBURGH 2015-12-23 CN claimed
US-20150306034-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS UNIV PITTSBURGH (US) 2015-10-29 US claimed
EP-2931260-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2015-10-21 EP claimed
US-20150231271-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING FARNESYLTHIOSALYCYLIC MOITIES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-08-20 US claimed
WO-2014093631-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-06-19 WO claimed
CN-114945572-A HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia 刘扶东 2022-08-26 CN disclosed
US-10376591-B2 Formulations and carrier systems including farnesylthiosalicylic moieties University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2019-08-13 US disclosed
US-20190038556-A1 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2019-02-07 US disclosed
US-10172795-B2 Formulations and carrier systems including compound interactive domains University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2019-01-08 US disclosed
WO-2006088767-A2 C10 CYCLOPROPYL ESTER SUBSTITUTED TAXANE COMPOSITIONS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-08-24 WO disclosed
US-20060189679-A1 C10 cyclopropyl ester substituted taxane compositions FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-08-24 US disclosed
US-20060189679-A1 C10 cyclopropyl ester substituted taxane compositions FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-08-24 US disclosed
WO-2006088767-A2 C10 CYCLOPROPYL ESTER SUBSTITUTED TAXANE COMPOSITIONS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-08-24 WO disclosed