Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362843 | 0.70 | CYP3A4 (0.38) | KMT2ACYP3A4 | |
| SCHEMBL13843144 | 0.69 | MEN1 (0.36) | CSNK2A2CSNK2A1KMT2AMEN1CASP1 | |
| SCHEMBL27360280 | 0.68 | CYP3A4 (0.33) | KMT2AMEN1CYP3A4 | |
| SCHEMBL27507447 | 0.67 | PSEN1 (0.38) | KMT2ACYP3A4 | |
| SCHEMBL27352531 | 0.67 | CA12 (0.33) | CYP3A4 | |
| SCHEMBL28889147 | 0.65 | KMT2A (0.50) | KMT2AMEN1 | |
| SCHEMBL25962050 | 0.64 | MEN1 (0.37) | CSNK2A2CSNK2A1KMT2AMEN1CASP1 | |
| SCHEMBL11844069 | 0.64 | NPSR1 (0.59) | KMT2AMEN1 | |
| SCHEMBL6065065 | 0.64 | MEN1 (0.39) | CSNK2A2CSNK2A1KMT2AMEN1CASP1 | |
| SCHEMBL8587614 | 0.62 | MEN1 (0.41) | CSNK2A2CSNK2A1KMT2AMEN1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057091-C | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| CN-1148390-A | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 1997-04-23 | — | — | CN | disclosed |