Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352531 | 0.84 | CA12 (0.33) | CYP3A4ALDH1A1KDM4ESNCACA1 | |
| SCHEMBL27362843 | 0.75 | CYP3A4 (0.38) | CYP3A4ALDH1A1KDM4ESNCAKMT2A | |
| SCHEMBL28889147 | 0.69 | KMT2A (0.50) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL27363793 | 0.68 | CSNK2A2 (0.32) | CYP3A4KMT2AMEN1 | |
| SCHEMBL797852 | 0.66 | — | — | |
| SCHEMBL27362838 | 0.65 | ALDH1A1 (0.39) | CYP3A4ALDH1A1SNCAKMT2AMEN1 | |
| SCHEMBL10690119 | 0.64 | — | — | |
| SCHEMBL9547338 | 0.64 | — | — | |
| SCHEMBL88871 | 0.64 | CHRNB2 (0.54) | CYP3A4ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL27360279 | 0.64 | CYP3A4 (0.33) | CYP3A4NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057091-C | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| CN-1148390-A | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 1997-04-23 | — | — | CN | disclosed |