Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decarboxylated Derivative SCHEMBL28037171 | 0.87 | CYP2D6 (0.53) | CYP2D6ADH1BADH1CADH1AADH4 | |
| SCHEMBL14417956 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL131302 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL15444322 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| Decarboxylated Derivative SCHEMBL9465 | 0.86 | — | — | |
| SCHEMBL19099823 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL3536114 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL14417464 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL22078896 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA | |
| SCHEMBL13893972 | 0.86 | CYP2D6 (0.54) | CYP2D6SIGMAR1PLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066712-C | Prolinamide derivatives | MITSUBISHI CHEM CORP (JP) | 2001-06-06 | — | — | CN | disclosed |