Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444322 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL18102722 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL19992007 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL14417464 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL13893972 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL3536114 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| Decarboxylated Derivative SCHEMBL9465 | 1.00 | — | — | |
| SCHEMBL19099823 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| SCHEMBL22078896 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT | |
| Decarboxylated Derivative SCHEMBL5183307 | 1.00 | CYP2D6 (0.54) | CYP2D6SIGMAR1NCF1PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | VILNIUS UNIVERSITY (LT) | 2025-03-11 | — | — | US | disclosed |
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20240132467-A1 | BENZIMIDAZOLE DERIVATIVES FOR TREATING RESPIRATORY DISEASE | TMEM16A LIMITED (GB) | 2024-04-25 | — | — | US | disclosed |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | VILNIUS UNIVERSITY (LT) | 2024-01-04 | — | — | US | disclosed |
| EP-4299062-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| EP-4259607-A1 | BENZIMIDAZOLE DERIVATIVES FOR TREATING RESPIRATORY DISEASE | TMEM16A LIMITED (GB) | 2023-10-18 | — | — | EP | disclosed |
| CN-116745267-A | Benzimidazole derivatives for the treatment of respiratory diseases | 跨膜蛋白16A有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11566025-B2 | Viral replication inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-01-31 | — | — | US | disclosed |
| WO-2022266473-A1 | SMALL MOLECULE DISRUPTORS OF PROTEIN INTERACTIONS IN HISTONE DEACETYLASE COMPLEXES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| CN-115124492-A | Process for synthesizing tetraglycidyl amine epoxy resin by continuous method | 上海华谊树脂有限公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-0199986-B1 | BENZISOSELENAZOLONYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1990-04-25 | — | — | EP | disclosed |
| US-4873350-A | Diselenobis-benzoic acid amides of primary and secondary amines and processes for the treatment of diseases in humans caused by a cell injury | A NATTERMANN & CIE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0198277-B1 | DISELENO-BIS-BENZAMIDES OF PRIMARY AND SECONDARY AMINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1989-05-03 | — | — | EP | disclosed |
| US-4774252-A | ANTIINFLAMMATORY AGENTS | A. NATTERMANN & CIE GMBH (DE) | 1988-09-27 | — | — | US | disclosed |
| EP-0199986-A1 | Benzisoselenazolonyl derivatives, process for their preparation and pharmaceutical compositions containing them | A. Nattermann & Cie. GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |
| EP-0198277-A1 | Diseleno-bis-benzamides of primary and secondary amines, processes for their production and pharmaceutical preparations containing them | A. Nattermann & Cie. GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |
| US-4491671-A | Process for the preparation of N-substituted imido-dicarboxylic acid diaryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | disclosed |
| US-4348331-A | FROM THE HYDROCHLORIDE OF A PRIMARY AMINE AND AN ARYL ESTER HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4024274-A | Benzylamine derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4001284-A | PRIMARY AMINES, 2,4-DIPHENOXY-5-SULFAMOYLBENZOIC ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566025-B2 | Viral replication inhibitors | EIF2AK2, MAVS, ZC3HAV1 | CYP2D6 3515/4885SIGMAR1 3557/4885NCF1 1198/4885 |
| US-20240132467-A1 | BENZIMIDAZOLE DERIVATIVES FOR TREATING RESPIRATORY DISEASE | TMEM109, CFTR, TMEM164 | CYP2D6 1577/4885SIGMAR1 1082/4885NCF1 2618/4885 |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | APP, APBA1, IAPP | CYP2D6 2920/4885SIGMAR1 3698/4885NCF1 2819/4885 |
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | APP, APBA1, IAPP | CYP2D6 2920/4885SIGMAR1 3698/4885NCF1 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.