SCHEMBL27363871

SCHEMBL27363871

CCCc1ccc(Sc2ccc(N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
TSHR P16473 2/20 0.58
MAPK1 P28482 1/20 0.58
GFER P55789 1/20 0.52
MAOB P27338 4/20 0.45
MAOA P21397 2/20 0.45
CA2 P00918 1/20 0.42
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
CYP19A1 P11511 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HTR2A P28223 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577213 0.89 LPL (0.48) CYP3A4TSHRMAPK1CA2LPL
SCHEMBL5962 0.87 GFER (0.68) CYP3A4TSHRGFERMAOBMAOA
SCHEMBL29155827 0.84 GFER (0.65) CYP3A4TSHRGFERMAOBMAOA
SCHEMBL22360078 0.83 TAAR1 (0.48) CA2LPLLIPGTAAR1
Ethylamine SCHEMBL27859952 0.82 GFER (0.62) CYP3A4TSHRGFERMAOBMAOA
SCHEMBL27362284 0.82 HTR2C (0.60) CYP3A4TSHRMAPK1MAOBMAOA
SCHEMBL19938060 0.81 SLC6A4 (0.53) MAOBMAOACA2ALDH1A1LPL
4,4'-Thiodianiline SCHEMBL27779878 0.80 TSHR (0.67) CYP3A4TSHRMAPK1GFERMEN1
4,4'-Methylenedianiline SCHEMBL11590275 0.80 CYP3A4 (0.67) CYP3A4TSHRGFERMAOBMAOA
SCHEMBL1696232 0.80 GFER (0.59) CYP3A4TSHRGFERMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1066754-C Thermoplastic resin composition and process for molding the same NEW JAPAN CHEM CO LTD (JP) 2001-06-06 CN disclosed