SCHEMBL27363975

SCHEMBL27363975

c1ccc(-c2ccc3oc4c(-c5ccccc5)nc(-c5cc6ccccc6cc5-n5c6ccccc6c6c7ccccc7ccc65)nc4c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAPK3 P27361 1/20 0.32
AHR P35869 1/20 0.32
PAX8 Q06710 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
PRKDC P78527 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27363995 0.93 PIM1 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27364028 0.93 ALDH1A1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363971 0.92 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL30019744 0.90 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27081847 0.90 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363968 0.89 PIM1 (0.38) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27364142 0.88 PIM1 (0.40) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363978 0.86 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363951 0.85 ALDH1A1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363988 0.84 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed