SCHEMBL27364020

SCHEMBL27364020

CCCC/C(=C\C=C\C=Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.49
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGES O14684 2/20 0.43
ALOX5 P09917 2/20 0.43
PPARG P37231 1/20 0.43
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
HDAC3 O15379 2/20 0.43
EGFR P00533 1/20 0.43
MAOB P27338 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375312 0.94 GRIK1 (0.55) GRIK1KDM4EMEN1KMT2APTGES
SCHEMBL23934240 0.94 GRIK1 (0.55) GRIK1KDM4EMEN1KMT2APTGES
SCHEMBL393958 0.90 GRIK1 (0.54) GRIK1KDM4EMEN1KMT2APTGES
Maleic Acid SCHEMBL8995943 0.89 GRIK1 (0.50) GRIK1KDM4EMEN1KMT2APTGES
SCHEMBL905410 0.88 TDP1 (0.52) GRIK1KDM4EMEN1KMT2ALMNA
SCHEMBL10904990 0.88 TDP1 (0.52) GRIK1KDM4EMEN1KMT2ALMNA
SCHEMBL7780529 0.88 TDP1 (0.52) GRIK1KDM4EMEN1KMT2ALMNA
SCHEMBL7107526 0.88 TDP1 (0.52) GRIK1KDM4EMEN1KMT2ALMNA
SCHEMBL11445983 0.88 TDP1 (0.52) GRIK1KDM4EMEN1KMT2ALMNA
Methacrylic Acid SCHEMBL2912337 0.87 GRIK1 (0.49) GRIK1KDM4EMEN1KMT2APTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1252824-A Composition containing slip agent and anti-caking agent DOW CHEMICAL CO (US) 2000-05-10 CN claimed
CN-101842434-A Polypropylene composition, method of making the same, and articles made therefrom DOW GLOBAL TECHNOLOGIES INC 2010-09-22 CN disclosed
CN-100516120-C Olefin block copolymers, production processes of same and use thereof MITSUI CHEMICALS INC (JP) 2009-07-22 CN disclosed
CN-100453566-C Ethylene (co) polymers and use thereof MITSUI CHEMICALS INC (JP) 2009-01-21 CN disclosed
CN-100436492-C Olefin polymer MITSUI CHEMICALS INC (JP) 2008-11-26 CN disclosed
CN-100357330-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-12-26 CN disclosed
CN-100335509-C Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-09-05 CN disclosed
CN-1737017-A Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1737016-A Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1219800-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2005-09-21 CN disclosed
CN-1362972-A Olefin polymer and process for producing the same MITSUI CHEMICALS INC (JP) 2002-08-07 CN disclosed
CN-1342715-A Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2002-04-03 CN disclosed
CN-1314921-A Ethylene (co) polymers and their use MITSUI CHEMICALS INC (JP) 2001-09-26 CN disclosed
CN-1313880-A Soft syndiotactic polypropylene compositions and shaped products MITSUI CHEMICALS INC (JP) 2001-09-19 CN disclosed
CN-1300787-A Propylene ethylene block copolymer, resin composition and blown plastic articles IDEMITSU PETROCHEMICAL CO (JP) 2001-06-27 CN disclosed
CN-1062576-C polypropylene composition and uses thereof MITSUT PETROCHEMICAL IND LTD (JP) 2001-02-28 CN disclosed
CN-1252824-A Composition containing slip agent and anti-caking agent DOW CHEMICAL CO (US) 2000-05-10 CN disclosed
CN-1219941-A Crystalline polypropylene, process for preparing same, polypropylene composition, and thermoformed article MITSUI CHEMICALS INC (JP) 1999-06-16 CN disclosed
CN-1213391-A Thermoplastic resin composition and film made from the composition MITSUI CHEMICALS INC (JP) 1999-04-07 CN disclosed
CN-1139130-A Polypropylene composition and uses thereof MITSUT PETROCHEMICAL IND LTD (JP) 1997-01-01 CN disclosed