Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579036 | 0.81 | TLR8 (0.54) | CYSLTR1CYSLTR2 | |
| SCHEMBL10615795 | 0.80 | STAT3 (0.51) | PIN1CYP2D6 | |
| SCHEMBL28691857 | 0.80 | KDM4E (0.37) | HRH4PIN1CYSLTR1CYSLTR2 | |
| Phosphine SCHEMBL27716021 | 0.79 | TLR8 (0.52) | CYSLTR1CYSLTR2 | |
| SCHEMBL3433191 | 0.79 | TLR8 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL27372800 | 0.79 | HTR2C (0.49) | PIN1IDO1 | |
| SCHEMBL7044155 | 0.77 | TLR8 (0.51) | HRH4CYSLTR1CYSLTR2 | |
| SCHEMBL28700302 | 0.77 | KDM4E (0.37) | HRH4PIN1CYSLTR1CYSLTR2 | |
| SCHEMBL28015168 | 0.77 | CYP1B1 (0.38) | HRH4CYSLTR1CYSLTR2 | |
| SCHEMBL716117 | 0.76 | TSHR (0.50) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | disclosed |