SCHEMBL27364076

SCHEMBL27364076

c1ccc(-c2nc(-c3ccccc3)c3c(n2)oc2ccc(-c4ccc(-n5c6ccccc6c6cc7ccccc7cc65)c5oc6ccccc6c45)cc23)cc1

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
CSF1R P07333 1/20 0.30
PDGFRB P09619 1/20 0.30
MAPT P10636 1/20 0.30
KIT P10721 1/20 0.30
FLT3 P36888 1/20 0.30
KMT2A Q03164 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27364109 0.94 MEN1 (0.31) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL27364080 0.94
SCHEMBL27363908 0.93 PIM1 (0.31)
SCHEMBL27364078 0.92
SCHEMBL27364074 0.90 ALDH1A1 (0.36) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL27364114 0.90 PRKDC (0.33)
SCHEMBL27364084 0.89
SCHEMBL27363918 0.89 PIM1 (0.32)
SCHEMBL27364143 0.89 PRKDC (0.33) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL27364082 0.86 MEN1 (0.31) MEN1CSF1RPDGFRBMAPTKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed