Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | CA7 | P43166 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.65 |
| ▸ | XDH | P47989 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26886774 | 0.89 | LCK (0.54) | LCKCA12CA1CA2CA7 | |
| SCHEMBL29066219 | 0.87 | LMNA (0.51) | LCKCA12CA1CA2CA7 | |
| SCHEMBL4795518 | 0.87 | BCL2L1 (0.54) | LCKCA12CA1CA2CA7 | |
| SCHEMBL2635623 | 0.87 | LMNA (0.51) | LCKCA12CA1CA2CA7 | |
| SCHEMBL26886782 | 0.86 | LCK (0.51) | LCKCA12CA1CA2CA7 | |
| SCHEMBL161776 | 0.84 | LMNA (0.56) | LCKCA12CA1CA2CA7 | |
| SCHEMBL31120448 | 0.83 | LCK (0.67) | LCKCA12CA1CA2CA7 | |
| SCHEMBL7220681 | 0.83 | LCK (0.67) | LCKCA12CA1CA2CA7 | |
| SCHEMBL29086835 | 0.82 | LCK (0.57) | LCKCA12CA1CA2CA7 | |
| SCHEMBL22559455 | 0.80 | LCK (0.59) | LCKCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073081-C | Naphthol derivatives and process for producing the same | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2001-10-17 | — | — | CN | disclosed |
| CN-1155882-A | Naphthol derivatives and process for producing the same | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1997-07-30 | — | — | CN | disclosed |