Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024074 | 0.87 | KMT2A (0.55) | KMT2AMAPTSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL434556 | 0.84 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL6668242 | 0.84 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL16241898 | 0.84 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL29412194 | 0.84 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL9616117 | 0.83 | KDM4E (0.44) | SMN1; SMN2NPSR1TSHR | |
| SCHEMBL28024499 | 0.83 | KMT2A (0.56) | KMT2AMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL11847525 | 0.82 | MAPT (0.58) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL9340109 | 0.82 | KMT2A (0.58) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL6957827 | 0.82 | KMT2A (0.58) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928905-A | As oxytocins/pitressin V1a receptor antagonist pyrrolidin derivatives | 奥布赛瓦股份公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-109748836-A | As oxytocins/pitressin V1a receptor antagonist pyrrolidin derivatives | 奥布赛瓦股份公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-102086273-B | Cellulose ester resin composition, optical film employing the same and polarizer for LCD device | DAINIPPON INK & CHEMICALS | 2014-11-26 | — | — | CN | disclosed |
| CN-102086273-A | Cellulose ester resin composition, optical film employing the same and polarizer for LCD device | DAINIPPON INK & CHEMICALS | 2011-06-08 | — | — | CN | disclosed |
| CN-1080257-C | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-06 | — | — | CN | disclosed |
| CN-1064042-C | Intermediate of benzazepine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1040748-C | Benzazepine derivatives, pharmaceutical compositions and intermediates thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-11-18 | — | — | CN | disclosed |
| CN-1198437-A | Intermediate of benzazepine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1998-11-11 | — | — | CN | disclosed |
| CN-1129934-A | Benzazepine derivatives, pharmaceutical compositions and intermediates thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1996-08-28 | — | — | CN | disclosed |
| CN-1123545-A | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-29 | — | — | CN | disclosed |