Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024074 | 0.84 | KMT2A (0.55) | KMT2AALOX15NPSR1MAPTRAB9A | |
| SCHEMBL27364543 | 0.83 | KMT2A (0.58) | KMT2AGAAUSP2ALOX15NPSR1 | |
| SCHEMBL14055345 | 0.78 | KMT2A (0.59) | KMT2AKDM4EGAAALDH1A1USP2 | |
| SCHEMBL21999712 | 0.78 | KMT2A (0.70) | KMT2AKDM4EGAAALDH1A1USP2 | |
| SCHEMBL14335116 | 0.78 | KDM4E (0.59) | KMT2AKDM4EGAAALDH1A1USP2 | |
| SCHEMBL9139340 | 0.75 | KMT2A (0.57) | KMT2AKDM4EGAAALDH1A1USP2 | |
| SCHEMBL10924560 | 0.75 | KMT2A (0.47) | KMT2AKDM4EGAAUSP2ALOX15 | |
| SCHEMBL28024056 | 0.75 | ESR1 (0.55) | KMT2AGAAALDH1A1NPSR1PKM | |
| SCHEMBL21771872 | 0.74 | KMT2A (0.56) | KMT2AKDM4EGAAALDH1A1USP2 | |
| SCHEMBL22090951 | 0.74 | KMT2A (0.56) | KMT2AKDM4EGAAALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |