Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.72 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.64 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931730 | 0.91 | NR4A2 (0.60) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL4485057 | 0.91 | NR4A2 (0.68) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL10397437 | 0.91 | NR4A2 (0.68) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL3734053 | 0.89 | NR4A2 (0.58) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL2810907 | 0.89 | GPR84 (0.60) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL27853728 | 0.89 | NR4A2 (0.58) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL28371975 | 0.89 | NR4A2 (0.62) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL6418495 | 0.87 | NR4A2 (0.72) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL31026078 | 0.87 | NR4A2 (0.58) | NR4A2CREBBPGPR84ALDH1A1HPGD | |
| SCHEMBL28984928 | 0.87 | NR4A2 (0.58) | NR4A2CREBBPGPR84ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |