SCHEMBL27365375

SCHEMBL27365375

CC(CCCCC(=O)O)C(=O)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ELANE P08246 1/20 0.43
HDAC1 Q13547 3/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
PPARA Q07869 3/20 0.41
TBXAS1 P24557 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27365373 0.89 PRSS1 (0.50) ATML3MBTL1ELANEMAPTTDP1
SCHEMBL18098074 0.86 ELANE (0.44) ATML3MBTL1ELANEMAPTTDP1
SCHEMBL2291004 0.86 PRSS1 (0.48) ATML3MBTL1ELANETDP1MAPK1
SCHEMBL12857956 0.84 EPOR (0.43) ATML3MBTL1ELANETDP1
SCHEMBL11699133 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR
SCHEMBL2294967 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR
SCHEMBL29266799 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR
SCHEMBL1900961 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR
SCHEMBL2294692 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR
SCHEMBL27994629 0.84 PRSS1 (0.50) L3MBTL1TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1066135-C Ysnthetic excitatory amino acids LILLY CO ELI (US) 2001-05-23 CN disclosed
CN-1123272-A Ysnthetic excitatory amino acids LILLY CO ELI (US) 1996-05-29 CN disclosed