Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732374 | 0.82 | LRRK2 (0.42) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL4725461 | 0.82 | ACP1 (0.47) | MEN1PKMKMT2AMAPTKDM4E | |
| SCHEMBL31197376 | 0.82 | ACP1 (0.47) | MEN1PKMKMT2AMAPTKDM4E | |
| SCHEMBL31197374 | 0.82 | ACP1 (0.47) | MEN1PKMKMT2AMAPTKDM4E | |
| SCHEMBL27365630 | 0.81 | ALDH1A1 (0.41) | MEN1PKMKMT2AMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL5442383 | 0.80 | ACP1 (0.46) | MEN1PKMKMT2AMAPTKDM4E | |
| SCHEMBL16250225 | 0.79 | CA1 (0.49) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL19475472 | 0.76 | TOP2A (0.55) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL5616954 | 0.76 | ELANE (0.52) | MEN1PKMKMT2AMAPTNPSR1 | |
| SCHEMBL4006211 | 0.75 | TOP2A (0.70) | MEN1PKMKMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |