Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779547 | 0.83 | NAMPT (0.39) | NAMPTCYP17A1ATRBRD9LCK | |
| SCHEMBL31363541 | 0.82 | LCK (0.47) | NAMPTCYP17A1ATRLCKCA1 | |
| SCHEMBL2107971 | 0.78 | NAMPT (0.48) | NAMPTCYP17A1ATRBRD9METAP1 | |
| SCHEMBL555073 | 0.78 | NAMPT (0.48) | NAMPTCYP17A1ATRBRD9LCK | |
| SCHEMBL22542766 | 0.77 | ATR (0.36) | NAMPTCYP17A1ATRBRD9LCK | |
| SCHEMBL17327940 | 0.77 | CYP17A1 (0.44) | NAMPTCYP17A1ATRBRD9CA1 | |
| SCHEMBL6503172 | 0.77 | NAMPT (0.39) | NAMPTCYP17A1ATRBRD9LCK | |
| SCHEMBL849561 | 0.76 | LCK (0.46) | BRD9LCKCA1CA12CA9 | |
| SCHEMBL20519396 | 0.76 | NAMPT (0.38) | NAMPTCYP17A1ATRBRD9LCK | |
| SCHEMBL28432967 | 0.75 | NAMPT (0.39) | NAMPTCYP17A1ATRBRD9LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |