Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27365853 | 0.82 | NAMPT (0.39) | LCKATRNAMPTCYP17A1CA12 | |
| SCHEMBL3131919 | 0.81 | LCK (0.60) | LCKCA12CA1CA9 | |
| SCHEMBL20865564 | 0.81 | LCK (0.50) | LCKATRCYP17A1CA12CA1 | |
| SCHEMBL24574915 | 0.81 | LCK (0.60) | LCKATR | |
| SCHEMBL5779547 | 0.80 | NAMPT (0.39) | LCKATRNAMPTCYP17A1CA12 | |
| SCHEMBL17208821 | 0.80 | ATR (0.51) | LCKATRNAMPTCYP17A1 | |
| SCHEMBL17528556 | 0.80 | LCK (0.49) | LCKATRCA12CA1CA9 | |
| SCHEMBL31363315 | 0.79 | LCK (0.42) | LCKATRCA12CA1CA9 | |
| SCHEMBL30830461 | 0.79 | LCK (0.48) | LCKATRCA12CA1CA9 | |
| SCHEMBL25243093 | 0.79 | LCK (0.62) | LCKCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |