Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859994 | 0.81 | TSHR (0.38) | TSHRKDM1AMAOBPOLB | |
| SCHEMBL6621761 | 0.81 | CXCR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL27493534 | 0.80 | KDM1A (0.38) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL16015416 | 0.78 | PRCP (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL13696621 | 0.78 | PRCP (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL9109553 | 0.78 | MEN1 (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL9955174 | 0.78 | MEN1 (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL18124794 | 0.78 | KDM1A (0.37) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL931762 | 0.78 | MEN1 (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL9955172 | 0.78 | MEN1 (0.34) | TSHRKDM1AMAOAMAOBCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055467-C | New taxoids, their preparation and pharmaceutical compositions containing them | RHONE POULENG RORER S A (FR) | 2000-08-16 | — | — | CN | disclosed |
| CN-1094720-A | New taxoids, its preparation and the pharmaceutical composition that contains them | RHONE POULENC RORER SA (FR) | 1994-11-09 | — | — | CN | disclosed |