SCHEMBL27366108

SCHEMBL27366108

CN(CCc1cccc2cccc(O)c12)C1CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 14/20 1.00
HTR2C P28335 10/20 0.42
HTR2B P41595 7/20 0.41
HTR1A P08908 3/20 0.40
DRD3 P35462 3/20 0.40
DRD1 P21728 1/20 0.40
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HTR1E P28566 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
HTR7 P34969 1/20 0.40
HTR5A P47898 1/20 0.40
HTR6 P50406 1/20 0.40
KDM4E B2RXH2 1/20 0.38
DRD2 P14416 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366008 0.81 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1ADRD3
SCHEMBL31331990 0.80 HTR2A (0.67) HTR2AHTR6KDM4E
SCHEMBL27366104 0.80 HTR2A (0.67) HTR2AHTR6KDM4E
SCHEMBL30916156 0.78 HTR2A (0.71) HTR2AHTR2CHTR2BHTR1ADRD3
SCHEMBL22612485 0.78 HTR2A (0.71) HTR2AHTR2CHTR2BHTR1ADRD3
SCHEMBL25028217 0.78 HTR2A (0.64) HTR2AHTR2CHTR2BHTR1ADRD3
SCHEMBL7046427 0.77 HTR2A (0.63) HTR2AHTR1AKDM4E
SCHEMBL27366015 0.77 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1ADRD3
Hydrochloric Acid SCHEMBL27085086 0.77 HTR2A (0.69) HTR2AHTR2CHTR2BHTR1ADRD3
SCHEMBL27365901 0.76 HTR2A (0.61) HTR2AHTR2CHTR1ADRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed