SCHEMBL27366008

SCHEMBL27366008

CN(C)CCc1cccc2cccc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 14/20 1.00
HTR2C P28335 9/20 0.58
HTR2B P41595 5/20 0.58
HTR1A P08908 2/20 0.58
DRD1 P21728 1/20 0.58
HTR1D P28221 1/20 0.58
HTR1B P28222 1/20 0.58
HTR1E P28566 1/20 0.58
ADORA2A P29274 1/20 0.58
ADORA2B P29275 1/20 0.58
HTR7 P34969 1/20 0.58
DRD3 P35462 1/20 0.58
HTR5A P47898 1/20 0.58
HTR6 P50406 1/20 0.58
TAAR1 Q96RJ0 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366015 0.85 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL27366102 0.83 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL27366108 0.81 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL36797 0.79 HTR2A (0.65) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL7862036 0.78 HTR2A (0.64) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL27366565 0.77 HTR2A (0.62) HTR2AHTR2CTAAR1
SCHEMBL18860639 0.77 HTR2A (0.62) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL30883880 0.76 HTR2A (0.62) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL31331965 0.76 HTR2A (0.61) HTR2AHTR1AHTR7HTR6
SCHEMBL27365914 0.76 HTR2A (0.61) HTR2AHTR1AHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed