Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453740 | 0.80 | NPC1 (0.45) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL20226039 | 0.79 | PTGS2 (0.44) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27977351 | 0.77 | NPC1 (0.42) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL27921671 | 0.77 | HTT (0.42) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL27921668 | 0.76 | HTT (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27771834 | 0.73 | HPGD (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28866100 | 0.73 | HPGD (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27846452 | 0.73 | HPGD (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL17610553 | 0.71 | MAPK1 (0.46) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6560508 | 0.71 | HPGD (0.54) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055922-C | Lactone compound and process of production thereof | TEIJIN LTD (JP) | 2000-08-30 | — | — | CN | disclosed |
| CN-1108244-A | Lactone compound and process of production thereof | TEIJIN LTD (JP) | 1995-09-13 | — | — | CN | disclosed |