SCHEMBL27366322

SCHEMBL27366322

CCCCC1=Cc2c(C)ccc(C)c2C1O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.33
SKP2 Q13309 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8617951 0.80 SKP2 (0.31) SKP2
Hydrochloric Acid SCHEMBL8361304 0.74
Hydrochloric Acid SCHEMBL8359410 0.74
SCHEMBL8617624 0.69
Hydrochloric Acid SCHEMBL7642716 0.67
SCHEMBL27677590 0.66 NPC1 (0.32) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL10644406 0.64 TSHR (0.36) CYP3A4CYP2D6CYP2C9HPGDMAPK1
SCHEMBL3995610 0.63 TYR (0.55) TYRSKP2CYP3A4NPC1HPGD
SCHEMBL7044456 0.63
Hydrochloric Acid SCHEMBL27451937 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1065866-C Process for converting achiral meso form of ansa-metallocene complex into chiral racemic form BASF AG (DE) 2001-05-16 CN disclosed
CN-1190398-A Process for converting achiral meso form of ansa-metallocene complex into chiral racemic form BASF AG (DE) 1998-08-12 CN disclosed