Tyrosine

SCHEMBL27366389

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	11/20	0.41

▸	CALCR	P30988	3/20	0.40

▸	CRHR1	P34998	1/20	0.38

▸	CRHR2	Q13324	1/20	0.38

▸	VIPR2	P41587	2/20	0.37

▸	APLNR	P35414	1/20	0.37

▸	GCGR	P47871	3/20	0.37

▸	VIPR1	P32241	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Tyrosine SCHEMBL27498286	0.96	CALCR (0.40)	GLP1RCALCRCRHR1CRHR2VIPR2
Tryptophan SCHEMBL27331432	0.95	GLP1R (0.45)	GLP1RGCGR
Tryptophan SCHEMBL27505901	0.94	GLP1R (0.45)	GLP1RGCGR
Tryptophan SCHEMBL27700472	0.94	GLP1R (0.45)	GLP1RGCGR
Cystine SCHEMBL27445596	0.94	GLP1R (0.40)	GLP1RCALCRCRHR1CRHR2APLNR
Tryptophan SCHEMBL27448344	0.94	GLP1R (0.44)	GLP1RGCGR
Tryptophan SCHEMBL27645885	0.94	GLP1R (0.44)	GLP1RGCGR
Cystine SCHEMBL27684299	0.94	GLP1R (0.43)	GLP1RCALCRCRHR1CRHR2APLNR
Tyrosine SCHEMBL27295274	0.93	GLP1R (0.39)	GLP1RCALCRCRHR1CRHR2VIPR2
Tryptophan SCHEMBL27646591	0.93	GLP1R (0.45)	GLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-1055198-C	Process for selectively breeding and producing high-efficiency crop disease prevention and output increasing strain	UNIV BEIJING (CN)	2000-08-09	—	—	CN	claimed
CN-1055198-C	Process for selectively breeding and producing high-efficiency crop disease prevention and output increasing strain	UNIV BEIJING (CN)	2000-08-09	—	—	CN	disclosed