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Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL27498286

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 3/20 0.40
▸ GLP1R P43220 9/20 0.39
▸ CRHR1 P34998 1/20 0.38
▸ CRHR2 Q13324 1/20 0.38
▸ VIPR2 P41587 2/20 0.37
▸ GCGR P47871 3/20 0.37
▸ APLNR P35414 2/20 0.37
▸ VIPR1 P32241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL27366389 0.96 GLP1R (0.41) CALCRGLP1RCRHR1CRHR2VIPR2
Tyrosine SCHEMBL27295274 0.94 GLP1R (0.39) CALCRGLP1RCRHR1CRHR2VIPR2
Tryptophan SCHEMBL27645885 0.93 GLP1R (0.44) GLP1RGCGR
Tryptophan SCHEMBL27448344 0.93 GLP1R (0.44) GLP1RGCGR
Cystine SCHEMBL27445596 0.92 GLP1R (0.40) CALCRGLP1RCRHR1CRHR2GCGR
Tryptophan SCHEMBL27331432 0.92 GLP1R (0.45) GLP1RGCGR
Tryptophan SCHEMBL27700472 0.92 GLP1R (0.45) GLP1RGCGR
Tryptophan SCHEMBL27505901 0.92 GLP1R (0.45) GLP1RGCGR
Tryptophan SCHEMBL27646591 0.92 GLP1R (0.45) GLP1RGCGR
Tyrosine SCHEMBL27657510 0.91 TUBB4A (0.39) CALCRGLP1RCRHR1CRHR2VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1182368-A Immanomodulating compositions from bile for treatment of immune system disorders IMUTEC CORP (CA) 1998-05-20 — — CN disclosed