Diphenylacetylene

Diphenylacetylene

SCHEMBL27366616

C(#Cc1ccccc1)c1ccccc1.F

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.92
MAPT P10636 2/20 0.63
GRM5 P41594 6/20 0.57
CYP1A2 P05177 3/20 0.55
CYP3A4 P08684 3/20 0.55
CYP2C9 P11712 3/20 0.55
CYP2C19 P33261 3/20 0.55
NPC1 O15118 3/20 0.55
KDM4E B2RXH2 2/20 0.55
MEN1 O00255 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
KMT2A Q03164 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HSD17B10 Q99714 1/20 0.55
THPO P40225 2/20 0.52
KCNH2 Q12809 1/20 0.52
TSHR P16473 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylacetylene SCHEMBL27913124 0.96 APP (0.86) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL29188592 0.96 APP (1.00) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL960609 0.96 APP (1.00) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL68254 0.96 APP (1.00) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL23754282 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL28966277 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL29415615 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL9273707 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL31286315 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4
Diphenylacetylene SCHEMBL28768551 0.92 APP (0.92) APPMAPTGRM5CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101454375-B Crosslinkable prepolymer, process for production thereof, and use thereof ASAHI GLASS CO LTD 2012-06-06 CN claimed
CN-102093334-A Method for synthesizing condensed ring thiophene compounds UNIV ZHENGZHOU 2011-06-15 CN claimed
CN-1928668-B alignment method of negative dielectric anisotropic liquid crystal TOPPOLY OPTOELECTRONICS CORP 2010-05-12 CN claimed
CN-100519624-C Crosslinkable fluoroaromatic prepolymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN claimed
CN-109943350-A A kind of wide warm liquid-crystal composition and the high frequency assembly comprising it 武汉轻工大学 2019-06-28 CN disclosed
CN-103998414-B Liquid repellent compounds, polymers, compositions, articles, and methods of making the same ASAHI GLASS CO.,LTD. (JP) 2016-01-20 CN disclosed
CN-104080822-B Compound, polymkeric substance, solidification compound, coating composition and there is the article of cured film, the article with the pattern in lyophily region and liquid-repellant region and manufacture method thereof ASAHI GLASS CO.,LTD. (JP) 2016-01-06 CN disclosed
CN-104583857-A Prepolymer, curable material, coating composition, non-linear optical material, optical waveguide and light control device ASAHI GLASS CO LTD 2015-04-29 CN disclosed
CN-102093334-B Method for synthesizing condensed ring thiophene compounds UNIV ZHENGZHOU 2013-05-08 CN disclosed
CN-101454375-B Crosslinkable prepolymer, process for production thereof, and use thereof ASAHI GLASS CO LTD 2012-06-06 CN disclosed
CN-102093334-A Method for synthesizing condensed ring thiophene compounds UNIV ZHENGZHOU 2011-06-15 CN disclosed
CN-1928668-B alignment method of negative dielectric anisotropic liquid crystal TOPPOLY OPTOELECTRONICS CORP 2010-05-12 CN disclosed
CN-101454375-A Crosslinkable prepolymer, process for production thereof, and use thereof ASAHI GLASS CO LTD (JP) 2009-06-10 CN disclosed
CN-1928668-A Alignment method of negative dielectric anisotropic liquid crystal TOPPOLY OPTOELECTRONICS CORP (CN) 2007-03-14 CN disclosed
CN-1168365-A Cyclopentyl derivatives ROLIC AG (CH) 1997-12-24 CN disclosed
CN-1051926-A ELECTROOPTIC LIQUID CRYSTAL SYSTEM MERCK PATENT GES MIT BESSCHRAN (DE) 1991-06-05 CN disclosed