Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65856 | 0.84 | SMN1; SMN2 (0.64) | CYP2C9RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15772472 | 0.81 | KMT2A (0.64) | RAB9AMAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL22662913 | 0.81 | PTPN11 (0.51) | CYP2C9PLAUALDH1A1POLBTSHR | |
| SCHEMBL69025 | 0.80 | PTPN11 (0.68) | MAPTSMN1; SMN2PLAUALDH1A1TSHR | |
| SCHEMBL29365729 | 0.80 | PTPN11 (0.68) | MAPTSMN1; SMN2PLAUALDH1A1TSHR | |
| SCHEMBL27977252 | 0.79 | HPGD (0.73) | RAB9APLAUALDH1A1POLBPTPN11 | |
| SCHEMBL31107524 | 0.79 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL8732524 | 0.78 | PTPN11 (0.66) | MAPTSMN1; SMN2PLAUALDH1A1TSHR | |
| SCHEMBL4876319 | 0.78 | POLB (0.60) | CYP2C9PLAUALDH1A1POLBTSHR | |
| SCHEMBL7286109 | 0.78 | EPAS1 (0.48) | CYP2C9PLAUALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |