Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | CA2 | P00918 | 4/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | EGFR | P00533 | 2/20 | 0.77 |
| ▸ | FYN | P06241 | 2/20 | 0.77 |
| ▸ | MMP9 | P14780 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | CA4 | P22748 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | CA12 | O43570 | 1/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | CA3 | P07451 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL6544958 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL2783599 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL10340128 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL18351 | 0.88 | — | — | |
| Catechol SCHEMBL30088487 | 0.88 | — | — | |
| Catechol SCHEMBL29352716 | 0.88 | — | — | |
| Catechol SCHEMBL367675 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL11672589 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL30944695 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2TDP1ALOX15LMNA | |
| Catechol SCHEMBL25313512 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053437-C | Synthetic method for lisinopril | WUZHOU PHARMACEUTICAL FACTORY (CN) | 2000-06-14 | — | — | CN | disclosed |
| CN-1170002-A | Processes to produce-aluminoxane compositions | PHILLIPS PETROLEUM CO (US) | 1998-01-14 | — | — | CN | disclosed |
| CN-1140708-A | Synthetic method for lisinopril | WUZHOU PHARMACEUTICAL FACTORY (CN) | 1997-01-22 | — | — | CN | disclosed |
| CN-1112937-A | Metallocene catalyst systems, preparation and use | PHILLIPS PETROLEUM CO (US) | 1995-12-06 | — | — | CN | disclosed |