Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483841 | 0.84 | HDAC1 (0.51) | HDAC1HDAC6KDM4ELMNAMAPT | |
| SCHEMBL8656324 | 0.83 | HDAC1 (0.45) | HDAC1HDAC6PDE10ADGAT1 | |
| Hydrochloric Acid SCHEMBL8093008 | 0.82 | HDAC1 (0.44) | HDAC1HDAC6PDE10A | |
| SCHEMBL14736672 | 0.79 | HDAC1 (0.47) | HDAC1HDAC6PDE10ADGAT1NR1H3 | |
| Hydrochloric Acid SCHEMBL14736481 | 0.78 | HDAC1 (0.46) | HDAC1HDAC6PDE10ADGAT1NR1H3 | |
| SCHEMBL21670558 | 0.77 | HDAC1 (0.40) | HDAC1HDAC6PDE10ADGAT1KDM4E | |
| SCHEMBL11604895 | 0.75 | HDAC1 (0.53) | HDAC1HDAC6PDE10ADGAT1KDM4E | |
| SCHEMBL21872254 | 0.75 | HDAC1 (0.49) | HDAC1HDAC6PDE10ALMNANR1H3 | |
| SCHEMBL8830140 | 0.75 | HDAC1 (0.49) | HDAC1HDAC6PDE10AKMT2ANR1H3 | |
| SCHEMBL11217270 | 0.75 | HDAC1 (0.46) | HDAC1HDAC6KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088709-C | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 2002-08-07 | — | — | CN | disclosed |
| CN-1052984-C | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-05-31 | — | — | CN | disclosed |
| CN-1229082-A | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 1999-09-22 | — | — | CN | disclosed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | disclosed |