SCHEMBL21670558

SCHEMBL21670558

CO[Si](CCCn1cnc(-c2ccccc2)n1)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 6/20 0.40
HDAC6 Q9UBN7 6/20 0.40
PDE10A Q9Y233 1/20 0.39
KMT2A Q03164 2/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
DGAT1 O75907 2/20 0.35
NR1H3 Q13133 2/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
NR1H2 P55055 1/20 0.34
HPGDS O60760 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656324 0.77 HDAC1 (0.45) HDAC1HDAC6PDE10ADGAT1
SCHEMBL27367368 0.77 HDAC1 (0.45) HDAC1HDAC6PDE10AKMT2ALMNA
Hydrochloric Acid SCHEMBL8093008 0.76 HDAC1 (0.44) HDAC1HDAC6PDE10A
SCHEMBL23071448 0.75 USP2 (0.53) NPC1RAB9AALDH1A1L3MBTL1USP2
SCHEMBL21670581 0.74 KMT2A (0.34) KMT2ALMNAMEN1ALDH1A1
SCHEMBL14736672 0.73 HDAC1 (0.47) HDAC1HDAC6PDE10ADGAT1NR1H3
SCHEMBL26110088 0.73 HDAC1 (0.36) HDAC1HDAC6KMT2AMAPTDGAT1
SCHEMBL8830140 0.73 HDAC1 (0.49) HDAC1HDAC6PDE10AKMT2ANR1H3
SCHEMBL21634160 0.73 LMNA (0.30) LMNA
Hydrochloric Acid SCHEMBL14736481 0.72 HDAC1 (0.46) HDAC1HDAC6PDE10ADGAT1NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118475721-A Surface treatment liquid for metal 四国化成工业株式会社 2024-08-09 CN disclosed
CN-118414453-A Organic coating and method for producing same 四国化成工业株式会社 2024-07-30 CN disclosed
CN-114341401-B Surface treatment liquid for metal, concentrated liquid thereof, surface treatment liquid set for metal, surface treatment method, and method for producing printed wiring board 四国化成工业株式会社 2024-04-05 CN disclosed
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2023-06-20 US disclosed
EP-4026931-A1 METAL SURFACE TREATMENT SOLUTION AND LIQUID CONCENTRATE THEREOF, METAL SURFACE TREATMENT SOLUTION SET, METAL SURFACE TREATMENT METHOD, AND METHOD FOR MANUFACTURING PRINTED WIRING BOARD Shikoku Chemicals Corporation (JP) 2022-07-13 EP disclosed
CN-110475782-B Triazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2022-05-17 CN disclosed
EP-3608327-B1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2022-05-04 EP disclosed
CN-114341401-A Metal surface treatment liquid and concentrated liquid thereof, metal surface treatment liquid set and surface treatment method, and printed wiring board manufacturing method 四国化成工业株式会社 2022-04-12 CN disclosed
WO-2021045055-A1 METAL SURFACE TREATMENT SOLUTION AND LIQUID CONCENTRATE THEREOF, METAL SURFACE TREATMENT SOLUTION SET, METAL SURFACE TREATMENT METHOD, AND METHOD FOR MANUFACTURING PRINTED WIRING BOARD 四国化成工業株式会社 2021-03-11 WO disclosed
EP-3608327-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof CYP51A1, TLK2, SIK2 HDAC1 113/4885HDAC6 502/4885PDE10A 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.