SCHEMBL27367384

SCHEMBL27367384

O=NC1CNCCN1c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.53
SLC6A4 P31645 3/20 0.53
SLC6A3 Q01959 3/20 0.53
ADRB1 P08588 3/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
HTR2C P28335 12/20 0.42
HTR2B P41595 11/20 0.42
HTR2A P28223 6/20 0.42
SLC18A3 Q16572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL644545 0.75 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL2113970 0.74 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL710615 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL17884678 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL644788 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL2975110 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL1028438 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL17884836 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL2454158 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL988610 0.74 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104737022-A Systems and methods for multiple analyte analysis HOFFMANN LA ROCHE 2015-06-24 CN disclosed
CN-100504369-C Test strip with flared sample receiving chamber HOFFMANN LA ROCHE (CH) 2009-06-24 CN disclosed
CN-1842705-A Test strip with flared sample receiving chamber HOFFMANN LA ROCHE (CH) 2006-10-04 CN disclosed
CN-1054666-A Be used for the method for electrochemical determination of analyte or oxidoreducing enzyme and sensitive electrode system and for this reason and the compound that uses BOEHRINGER MANNHEIM GMBH (DE) 1991-09-18 CN disclosed