SCHEMBL644788

SCHEMBL644788

NC1CNCCN1c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.57
SLC6A4 P31645 3/20 0.57
SLC6A3 Q01959 3/20 0.57
ADRB1 P08588 2/20 0.47
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
HTR2C P28335 9/20 0.41
HTR2B P41595 8/20 0.41
HTR2A P28223 5/20 0.41
BPTF Q12830 1/20 0.39
SLC18A3 Q16572 1/20 0.39
HTR1A P08908 1/20 0.39
HTR7 P34969 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454158 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL7801022 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL988610 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL710615 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL17884678 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL2975110 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL1028438 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL17884836 0.78 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL1462574 0.77 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3ADRB1HTR3E
SCHEMBL27504254 0.77 SLC6A4 (0.69) SLC6A2SLC6A4SLC6A3ADRB1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10907085-B2 Swellable glass particles for reducing fluid flow in subterranean formations HALLIBURTON ENERGY SERVICES, INC. (US) 2021-02-02 US claimed
US-20160194544-A1 EPOXY RESIN FORMULATIONS CONTAINING AN IMPACT MODIFIER FOR USE IN SUBTERRANEAN WELLS HALLIBURTON ENERGY SERVICES, INC. 2016-07-07 US claimed
WO-2016024990-A1 NAPTHOL-BASED EPOXY RESIN ADDITIVES FOR USE IN WELL CEMENTING HALLIBURTON ENERGY SERVICES, INC. (US) 2016-02-18 WO claimed
WO-2015034473-A1 EPOXY RESIN FORMULATIONS CONTAINING AN IMPACT MODIFIER FOR USE IN SUBTERRANEAN WELLS HALLIBURTON ENERGY SERVICES, INC. (US) 2015-03-12 WO claimed
US-20130105162-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE TOUGHNESS OF SET CEMENTS SCHLUMBERGER TECHNOLOGY CORPORATION 2013-05-02 US claimed
US-20130109782-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE TOUGHNESS OF SET CEMENTS SCHLUMBERGER TECHNOLOGY CORPORATION 2013-05-02 US claimed
WO-2010086592-A1 METHODS FOR SERVICING WELL BORES WITH HARDENABLE RESIN COMPOSITIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2010-08-05 WO claimed
US-20100186956-A1 Methods for Servicing Well Bores with Hardenable Resin Compositions HALLIBURTON ENERGY SERVICES, INC. 2010-07-29 US claimed
US-7762329-B1 Methods for servicing well bores with hardenable resin compositions HALLIBURTON ENERGY SERVICES, INC. (US) 2010-07-27 US claimed
US-12265082-B2 Detecting microbial infection in wounds SYNOVO GMBH (DE) 2025-04-01 US disclosed
CN-114634483-B Antimitotic amides for the treatment of cancer and proliferative diseases 弗洛斯特生物科技有限公司 2024-08-13 CN disclosed
US-20240027454-A1 DETECTING MICROBIAL INFECTION IN WOUNDS SYNOVO GMBH (DE) 2024-01-25 US disclosed
US-11740241-B2 Construct including an anchor, an enzyme recognition site and an indicator region for detecting microbial infection in wounds SYNOVO GMBH (DE) 2023-08-29 US disclosed
CN-109564213-B Detecting microbial wound infection 西诺福有限公司 2023-01-31 CN disclosed
WO-2004024878-A2 STRUCTURALLY RIGID DOPAMINE D3 RECEPTOR SELECTIVE LIGANDS AND PROCESS FOR MAKING THEM GOV'T OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-03-25 WO disclosed
EP-0358284-B1 Derivatized alkanolamines as cardiovascular agents SCHERING AG (DE) 1997-08-20 EP disclosed
US-5051423-A Derivatized alkanolamines as cardiovascular agents SCHERING AG (DE) 1991-09-24 US disclosed
EP-0358284-A2 Derivatized alkanolamines as cardiovascular agents SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-14 EP disclosed
US-4885294-A AGRICULTURE, HUMANS PFIZER INC. (US) 1989-12-05 US disclosed
EP-0321131-A2 Triazole antifungal agents Pfizer Limited (GB) 1989-06-21 EP disclosed