Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504862 | 0.90 | MAPT (0.82) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL28691466 | 0.89 | MAPT (0.80) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL29350219 | 0.89 | MAPT (0.80) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL27367418 | 0.87 | MAPK1 (0.78) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL27506918 | 0.80 | MAPT (0.65) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL7454739 | 0.78 | MAPT (0.61) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL2089284 | 0.77 | NOTUM (0.68) | MAPTKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL28366398 | 0.77 | MAPT (0.61) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL9689377 | 0.77 | MAPT (0.62) | MAPTHPGDKMT2ATSHRHTT | |
| SCHEMBL3509692 | 0.75 | MAPT (0.60) | MAPTHPGDKMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049829-A2 | COMPOSITIONS AND METHODS FOR TREATING AND DETECTING CANCER | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-03-07 | — | — | WO | disclosed |
| CN-109942505-B | Isothiazolinone compounds and corresponding use | 华东理工大学 | 2021-08-27 | — | — | CN | disclosed |