Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367412 | 0.87 | MAPT (1.00) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL15504862 | 0.81 | MAPT (0.82) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL29350219 | 0.80 | MAPT (0.80) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL28691466 | 0.80 | MAPT (0.80) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL12369729 | 0.77 | PPARA (0.72) | MAPK1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL16510590 | 0.75 | HTT (0.52) | MAPK1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1456998 | 0.75 | MAPT (0.56) | MAPK1HTTKMT2AMAPTALDH1A1 | |
| SCHEMBL3481292 | 0.74 | CYP1A2 (0.66) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL9689377 | 0.73 | MAPT (0.62) | MAPK1HTTKMT2AMAPTHPGD | |
| SCHEMBL2356905 | 0.72 | S1PR1 (0.55) | MAPK1HTTKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049829-A2 | COMPOSITIONS AND METHODS FOR TREATING AND DETECTING CANCER | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-03-07 | — | — | WO | disclosed |