Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066245 | 0.77 | DRD2 (0.45) | TSHRHRH3DRD2DRD3 | |
| SCHEMBL7041642 | 0.74 | — | — | |
| SCHEMBL1780017 | 0.74 | — | — | |
| SCHEMBL10444846 | 0.74 | — | — | |
| SCHEMBL28269330 | 0.74 | — | — | |
| SCHEMBL4088733 | 0.74 | — | — | |
| SCHEMBL27328751 | 0.74 | — | — | |
| SCHEMBL22993416 | 0.69 | CYP2A6 (0.34) | TSHRCYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL14408900 | 0.69 | CYP19A1 (0.39) | TSHRCYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL23890511 | 0.69 | CYP2A6 (0.34) | TSHRCYP2A6ALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063281-A | 2-aryl-5- (trifluoromethyl) -2-pyrroline compounds and process for preparing insecticide, 2-aryl-1- (alkoxymethyl) -4-halo-5- (trifluoromethyl) pyrrole | AMERICAN CYANAMID CO (US) | 1992-08-05 | — | — | CN | disclosed |