Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141618 | 0.82 | SLC6A2 (0.61) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL20105596 | 0.82 | SLC6A2 (0.61) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL15921747 | 0.81 | SLC6A2 (0.59) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL15922321 | 0.81 | SLC6A2 (0.59) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL15921749 | 0.81 | SLC6A2 (0.59) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL2599478 | 0.76 | SLC6A2 (0.72) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL28091452 | 0.76 | SCN9A (0.35) | CHRNA7ALDH1A1TACR1PRCPSCN9A | |
| SCHEMBL25326855 | 0.74 | PRCP (0.39) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL166543 | 0.73 | PRCP (0.38) | TACR1PRCP | |
| SCHEMBL27870772 | 0.72 | SLC6A2 (0.38) | CHRNA7SLC6A2ADRA1AHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067683-C | Substituted morpholine derivatives and their use as therapeutic agents | MERK SHARP & DOHME LTD (GB) | 2001-06-27 | — | — | CN | claimed |
| CN-1139927-A | Substituted morpholine derivatives and their use as therapeutic agents | MERK SHARP & DOHME LTD (GB) | 1997-01-08 | — | — | CN | claimed |
| CN-1067683-C | Substituted morpholine derivatives and their use as therapeutic agents | MERK SHARP & DOHME LTD (GB) | 2001-06-27 | — | — | CN | disclosed |
| CN-1139927-A | Substituted morpholine derivatives and their use as therapeutic agents | MERK SHARP & DOHME LTD (GB) | 1997-01-08 | — | — | CN | disclosed |