Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208302 | 0.86 | HDAC2 (0.41) | — | |
| SCHEMBL2736995 | 0.83 | RORC (0.45) | — | |
| SCHEMBL12309618 | 0.82 | — | — | |
| SCHEMBL2737086 | 0.82 | CA12 (0.42) | — | |
| SCHEMBL14176090 | 0.78 | RORC (0.50) | — | |
| SCHEMBL14176077 | 0.78 | CA12 (0.45) | — | |
| SCHEMBL13594243 | 0.76 | RORC (0.43) | — | |
| SCHEMBL8880565 | 0.76 | CAPN1 (0.80) | CAPN1PTPN11CTSLCTSBDYRK1A | |
| SCHEMBL18584503 | 0.75 | FGFR1 (0.61) | PTPN11DYRK1A | |
| SCHEMBL2736544 | 0.75 | RARG (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |