Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122071 | 0.87 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL24847768 | 0.87 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL26171406 | 0.87 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL23797589 | 0.84 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL27368261 | 0.82 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL25833426 | 0.80 | DDB1 (0.72) | DDB1CRBNGAATSHR | |
| SCHEMBL21965448 | 0.80 | DDB1 (0.72) | DDB1CRBNGAATSHR | |
| SCHEMBL27091816 | 0.80 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL23551582 | 0.77 | DDB1 (0.68) | DDB1CRBNGAATSHR | |
| SCHEMBL23551585 | 0.77 | DDB1 (0.68) | DDB1CRBNGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026083-A1 | TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY | RIBON THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |