Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659188 | 0.82 | HDAC1 (0.39) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL8093101 | 0.82 | HTR2A (0.49) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL10968328 | 0.82 | HDAC1 (0.39) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL17784718 | 0.79 | HDAC1 (0.44) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL31370592 | 0.79 | HTR2A (0.62) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL7453176 | 0.78 | KDM4E (0.45) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL8739002 | 0.77 | MAPT (0.46) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL112354 | 0.75 | HTR2A (0.47) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL15105484 | 0.75 | KDM4E (0.44) | HDAC1HDAC2HDAC6RXFP1KDM4E | |
| SCHEMBL22746838 | 0.75 | ALDH1A1 (0.44) | HDAC1HDAC2HDAC6RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088709-C | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 2002-08-07 | — | — | CN | disclosed |
| CN-1052984-C | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-05-31 | — | — | CN | disclosed |
| CN-1229082-A | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 1999-09-22 | — | — | CN | disclosed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | disclosed |