Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165999 | 0.83 | TTR (0.57) | PTPRCTTRPOLBKMT2ATSHR | |
| SCHEMBL6172401 | 0.82 | PTPRC (0.50) | PTPRCKMT2ATSHRL3MBTL1KDM4E | |
| SCHEMBL9123084 | 0.76 | TSHR (0.52) | TTRPOLBTSHRTP53MAPT | |
| SCHEMBL13146658 | 0.74 | KDM4E (0.50) | PTPRCTTRPOLBKMT2ATSHR | |
| SCHEMBL27446402 | 0.74 | TTR (0.43) | PTPRCTTRPOLBKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9365820 | 0.74 | TSHR (0.50) | TTRPOLBTSHRTP53MAPT | |
| SCHEMBL8679181 | 0.73 | TTR (0.42) | PTPRCTTRPOLBKMT2ATSHR | |
| SCHEMBL30598693 | 0.72 | PTPRC (0.59) | PTPRCTTRKMT2ATP53MAPT | |
| SCHEMBL8221556 | 0.72 | PTPRC (0.59) | PTPRCTTRKMT2ATP53MAPT | |
| SCHEMBL6236495 | 0.72 | PTPRC (1.00) | PTPRCTTRPOLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063180-C | 5H, 10H-imidazo [1, 2 -a] indeno [1, 2 -e] pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE POULENC RORER SA (FR) | 2001-03-14 | — | — | CN | disclosed |
| CN-1180357-A | 5H, 10H-imidazo [1, 2-a ] indeno [1, 2-e ] pyrazin-4-one derivatives, preparation thereof and medicaments containing same | RHONE POULENC RORER SA (FR) | 1998-04-29 | — | — | CN | disclosed |