Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202782 | 0.82 | TTR (0.41) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL27368640 | 0.73 | PTPRC (0.56) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL8679189 | 0.72 | TTR (0.41) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL5645591 | 0.71 | TTR (0.37) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL8523526 | 0.71 | CYP2D6 (0.42) | PTPRCPOLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL27489549 | 0.69 | S100A4 (0.42) | PTPRCKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28220638 | 0.68 | TTR (0.34) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL27446402 | 0.68 | TTR (0.43) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL11726943 | 0.68 | TTR (0.40) | TTRPTPRCPOLBKMT2AKDM4E | |
| SCHEMBL27375147 | 0.67 | NQO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808142-A | Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |