SCHEMBL27368885

SCHEMBL27368885

CNCCCCN(C)CCNC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.50
PRMT3 O60678 1/20 0.50
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
PRMT8 Q9NR22 1/20 0.50
EPHX1 P07099 1/20 0.42
CHRM2 P08172 2/20 0.40
SIGMAR1 Q99720 5/20 0.39
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
KDM4A O75164 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
PAOX Q6QHF9 1/20 0.31
GGPS1 O95749 1/20 0.31
FDPS P14324 1/20 0.31
AGTR1 P30556 1/20 0.31
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29111926 0.97 PRMT1 (0.48) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL25075475 0.95 PRMT3 (0.48) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL11441189 0.92 PRMT1 (0.52) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL13540767 0.92 PRMT3 (0.46) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL1229873 0.92 EPHX1 (0.50) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL22946807 0.92 EPHX1 (0.50) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL19546063 0.92 PRMT3 (0.46) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL14178222 0.90 EPHX1 (0.48) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL16317337 0.89 PRMT3 (0.48) PRMT1PRMT3CARM1PRMT6PRMT8
SCHEMBL7780960 0.89 PRMT1 (0.55) PRMT1PRMT3CARM1PRMT6PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052702-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed