Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthene Carboxylic Acid SCHEMBL40617 | 0.98 | ATM (0.68) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL30011680 | 0.98 | ATM (0.68) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL11788347 | 0.96 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL5780275 | 0.96 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL9551091 | 0.96 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL27850229 | 0.96 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL9551090 | 0.94 | ATM (0.63) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL9551104 | 0.94 | ATM (0.63) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL2807858 | 0.92 | ATM (0.61) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL8819898 | 0.87 | ATM (0.56) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053443-C | Method for prepn. of probanthine bromide and its intermediate xanthene-9-carboxylic acid | WUZHOU PHARMACEUTICAL FACTORY (CN) | 2000-06-14 | — | — | CN | claimed |
| CN-101735192-A | Method for producing propantheline bromide intermediate Xanthene-9-carboxylic acid | NO 2 FACTORY OF SHANGHAI WUZHO | 2010-06-16 | — | — | CN | disclosed |
| CN-1053443-C | Method for prepn. of probanthine bromide and its intermediate xanthene-9-carboxylic acid | WUZHOU PHARMACEUTICAL FACTORY (CN) | 2000-06-14 | — | — | CN | disclosed |