Xanthene Carboxylic Acid

Xanthene Carboxylic Acid

SCHEMBL2807858

C1CCCCCCCCC1.C1CCCCCCCCC1.C1CCCCCCCCC1.O=C(O)C1c2ccccc2Oc2ccccc21

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.61
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
HDAC8 Q9BY41 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
HDAC9 Q9UKV0 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
TP53 P04637 2/20 0.53
CYP2C9 P11712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthene Carboxylic Acid SCHEMBL30011680 0.94 ATM (0.68) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL40617 0.94 ATM (0.68) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL11788347 0.92 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL5780275 0.92 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL27368945 0.92 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL27850229 0.92 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL9551091 0.92 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL9551104 0.90 ATM (0.63) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL9551090 0.90 ATM (0.63) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL8819898 0.84 ATM (0.56) ATMHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435966-B2 Associations of xanthogenates and cyclodextrins, and their use BIOSPHINGS AG (DE) 2013-05-07 US disclosed
US-20100240606-A1 ASSOCIATIONS OF XANTHOGENATES AND CYCLODEXTRINS, AND THEIR USE BIOSPHINGS AG (DE) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240606-A1 ASSOCIATIONS OF XANTHOGENATES AND CYCLODEXTRINS, AND THEIR USE HLA-DRB1, CXCR3, ANTXR2 ATM 938/4885HDAC3 2096/4885HDAC4 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.