Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 7/20 | 0.51 |
| ▸ | NRAS | P01111 | 2/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574347 | 1.00 | FLT3 (0.51) | FLT3NRASIRAK4 | |
| SCHEMBL27369163 | 0.93 | FLT3 (0.52) | FLT3NRASIRAK4 | |
| SCHEMBL24573932 | 0.93 | FLT3 (0.52) | FLT3NRASIRAK4 | |
| SCHEMBL31068065 | 0.92 | FLT3 (0.49) | FLT3NRAS | |
| SCHEMBL24574009 | 0.92 | FLT3 (0.47) | FLT3NRASIRAK4 | |
| SCHEMBL27362527 | 0.92 | FLT3 (0.47) | FLT3NRASIRAK4 | |
| SCHEMBL27369247 | 0.92 | FLT3 (0.49) | FLT3NRAS | |
| SCHEMBL24231338 | 0.87 | FLT3 (0.57) | FLT3NRASIRAK4 | |
| SCHEMBL25990668 | 0.87 | FLT3 (0.57) | FLT3NRASIRAK4 | |
| SCHEMBL31000223 | 0.86 | FLT3 (0.37) | FLT3NRASIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250431-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-28 | — | — | WO | disclosed |