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Sugi Predict / Compounds / SCHEMBL27369310

SCHEMBL27369310

SCHEMBL27369310

CCCCc1nc(Cl)c(CN)n1Cc1ccc2oc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)c(Br)c2c1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 3/20 0.58
▸ AGTR2 P50052 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9310433 0.94 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL9310400 0.93 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL9859377 0.92 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9310717 0.91 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL27351546 0.91 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL9309766 0.90 AGTR1 (0.58) AGTR1
SCHEMBL9309942 0.90 AGTR1 (0.59) AGTR1
SCHEMBL9310937 0.90 AGTR1 (0.56) AGTR1
SCHEMBL9310278 0.89 AGTR1 (0.58) AGTR1
SCHEMBL9311047 0.89 AGTR1 (0.58) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1052672-A Benzofuran derivative GLAXO GROUP LTD (GB) 1991-07-03 — — CN disclosed