SCHEMBL27369328

SCHEMBL27369328

O=C(O)N(c1ccc(Cl)cc1)C1CCNCC1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.47
CHRM3 P20309 4/20 0.47
TACR1 P25103 7/20 0.46
SLC6A4 P31645 6/20 0.44
SLC6A2 P23975 4/20 0.44
SLC6A3 Q01959 3/20 0.44
KCNH2 Q12809 1/20 0.44
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28001525 0.88 CHRM2 (0.52) CHRM2CHRM3KCNH2MEN1KMT2A
SCHEMBL8553350 0.85 SLC6A4 (0.51) CHRM2CHRM3SLC6A4SLC6A2SLC6A3
SCHEMBL27629277 0.83 NPC1 (0.54) CHRM2CHRM3SLC6A4SLC6A2SLC6A3
SCHEMBL926471 0.82 SLC6A4 (0.51) CHRM3TACR1SLC6A4SLC6A2SLC6A3
SCHEMBL27808928 0.82 SLC6A4 (0.50) TACR1SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL11466331 0.81 TACR1 (0.50) CHRM2CHRM3TACR1SLC6A4
SCHEMBL11447659 0.81 CHRM2 (0.58) CHRM2CHRM3TACR1SLC6A4SLC6A2
SCHEMBL17922972 0.80 SLC6A4 (0.40) TACR1SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL27808927 0.80 SLC6A4 (0.53) TACR1SLC6A4SLC6A2SLC6A3KCNH2
Hydrochloric Acid SCHEMBL9785700 0.80 CHRM2 (0.57) CHRM2CHRM3TACR1SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1054123-C Carbamic acid derivatives and method for preparing same ANZURIN PHARMACEUTICAL CO LTD (JP) 2000-07-05 CN disclosed
CN-1064075-A Carbamic acid derivative and preparation method thereof ANZURIN PHARMACEUTICAL CO LTD (JP) 1992-09-02 CN disclosed