Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891615 | 0.87 | MEN1 (0.54) | TRPM8MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL6621005 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL6160138 | 0.86 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL2712659 | 0.85 | MEN1 (0.62) | TRPM8MEN1KMT2AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL22797859 | 0.85 | SLC6A2 (0.53) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL27369328 | 0.85 | CHRM2 (0.47) | SLC6A4SLC6A2SLC6A3KCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL9785692 | 0.83 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL11407980 | 0.83 | MEN1 (0.65) | TRPM8MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15532038 | 0.82 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL926462 | 0.82 | OPRM1 (0.61) | SLC6A4SLC6A2SLC6A3KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497303-B1 | Carbamic acid derivatives and method for preparing the same | KYORIN SEIYAKU KK (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5300515-A | Cognition activators for brain disorders; alzheimer*s disease | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0497303-A2 | Carbamic acid derivatives and method for preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |