Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 19/20 | 0.44 |
| ▸ | NRAS | P01111 | 5/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | BLK | P51451 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27368266 | 1.00 | FLT3 (0.44) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL27368394 | 0.92 | FLT3 (0.40) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL27370364 | 0.92 | FLT3 (0.40) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL31000223 | 0.87 | FLT3 (0.37) | FLT3NRASIRAK4CDK7CCNH | |
| SCHEMBL24574347 | 0.86 | FLT3 (0.51) | FLT3NRASIRAK4 | |
| SCHEMBL27369249 | 0.86 | FLT3 (0.51) | FLT3NRASIRAK4 | |
| SCHEMBL27368267 | 0.86 | FLT3 (0.43) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL31068059 | 0.86 | FLT3 (0.50) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL24573964 | 0.86 | FLT3 (0.50) | FLT3NRASIRAK4IRAK1LCK | |
| SCHEMBL27368893 | 0.86 | FLT3 (0.50) | FLT3NRASIRAK4IRAK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250431-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-28 | — | — | WO | disclosed |